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Momordica charantia (Bitter melon) of the family Cucubitaceae has been reputed to be a medicinal plant finding its use in the treatment of an array of ailments including Diabetes,fevers, skin disorders and purportedly, some cancers.
In this piece we detail the effect of a 30-day ingestion of Momordica charantia on fertility and mitochondrial membrane permeability transition (MMPT) pore in experimental rats.
The MMPT pore is a crucial actor in the induction of apoptosis; the form of death a cell commits by itself and which has been found useful in the inhibition of cancer cells' proliferation.
Here, the discussion centers around the discovery of a link between the ingestion of the leaf decoction of Momordica charantia and opening of the permeability transition pore in normal rat liver mitochondria membrane as well as the attendant anti- fertility effects in tested rats.
Adeola Ehigie is a Membrane Biochemist who graduated from the University of Ibadan,Nigerian and teaches Biochemistry at the Ladoke Akintola University of Technology, Nigeria.
She had a stint at the Institute of Biophysics, CAS, China as an Organization for Women in Science for the developing World's Postgraduate Fellow.
She is happily married.
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